Anti aging mechanisms and to-do‘s

Anti aging mechanisms and to-do‘s

Genetic analysis, blood rejuvenation and the supposed miracle drug rapamycin: As our society grows older, the researchers measure the possibilities to give man more years of life.

Daily a glass of red wine

Not the age counts, but the attitude. At a time when people are getting older, we need to think about how we deal with age, how to make what we can do to live with joy and without pain. 30 percent of human longevity is inherited, according to the current expert opinion.

Man needs motivation

Rarely can be derived from the tests so simple tips. The interaction of the genetic factors is far too complex for this. For example, at least 60 genes are associated with the risk of myocardial infarction. Still, it is, of course, an exclusive form of preventive medicine. Health insurance funds hardly ever pay for such investigations.

The poison of aging

Stronger than the genes, so-called environmental factors influence our life expectancy. “Environment” means everything that surrounds us and what we absorb into our bodies. “The Teaching of the Poison of Aging”, a scientist trio from the US is writing an article in the journal “Cell”. Distilled from many other studies, the authors include the strongest age accelerators (“gerontogenes”): toxic chemicals, such as those occurring in cigarette smoke but also in exhaust gases, cell-damaging non-chemical influences such as rays, also of the sun, and – not to be underestimated – a strong or constant mental stress.

Whoever avoids these risk factors is already doing something against the accelerated inner and outer fold formation. In his bestseller with the programmatic title “How Not to Die”, the American doctor Michael Greger breaks down the measures against premature sickness on four guidelines: no smoking, not fat, a half an hour of movement On the day, while eating a few rules (lots of vegetables, rather full grain …).

Leave the comfort zone

Apparently, more and more people are orientated towards such tips. They leave their comfort zone and do a lot in their everyday lives, which strengthens their health. Because of a modern anti aging lifestyle, the expectation of life is increasing in countries like Germany and does not reach the border for a long time, say many renowned researchers.

Inflammatory reactions

Physicians decipher the mechanisms of aging more and more and can always name precise interactions. Many negative habits and influences – poor diet and stress stress, for example – heat chronic inflammation. The process in the vessels becomes particularly clear. Inflammatory medications damage sensitive cells lining the arteries and veins. Over time, the formerly smooth veins become rough and stiff and react more poorly to blood pressure fluctuations. There are fewer nutrients in the organs.

New active ingredient gives hope

But must it always be so exhausting? Yes, most doctors say. Alleged miracles such as the frequently praised hormone DHEA (dehydroepiandrosterone) could not prove their effectiveness scientifically; Nor is the vitamin C, a substance called Q7 or a class of proteins called sirtuine. According to the original and disappointed hope, they are to protect the vessels together with the red wine ingredient Resveratrol.

So it does not help: Self-initiative and self-discipline (in the case of non-smoking, better food, more sporadic) leads no way past. But research does not stop. Changing worms genetically in such a way that their natural lifespan stretches is only a finger exercise for the next generation of researchers in the laboratories. Techniques of this kind from the worm to the human being is, however, mere utopia.

More specific hopes are associated with a drug called rapamycin. As a drug he is already prescribed. In transplant patients who have received a new organ, rapamycin should prevent rejection of the transplanted foreign tissue.

Life expectancy in mice

The “revolutionary potential” that the US monthly magazine “The Atlantic” ascribes to rapamycin (also called sirolimus), has so far only been developed in very early experiments. In a mouse experiment the life expectancy of the treated animals rose by nine to 14 percent. Apparently, the substance that comes from a bacterium discovered on Rapa Nui (Easter Island) turns off aging cells.

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